ABSTRACT
Objective: To develop a GC-MS method for the simultaneous determination of six active constituents ( borneol, isoborneol, cinnamaldehyde, cinnamic acid, muscone and benzyl benzoate) in Shexiang Baoxin pills. Methods: A gas chromatogra-phy-mass spectrography (GC-MS) method was adopted using a DB-5 capillary column (30 m × 0. 25 mm,0. 1 μm). The column tem-perature was raised as the following program:the initial temperature was 70℃, maintained for 2 min, raised the temperature (5℃· min-1) to 150℃, maintained for 4 min and then raised the temperature (20℃·min-1) to 260℃, and maintained for 3 min. The range of mass-to-electric charge ratio was 10 to 425. Results:The calibration curves of borneol, isoborneol, cinnamaldehyde, cinnam-ic acid, muscone and benzyl benzoate were linear within the range of 0.022-22.000 μg·ml-1(r=0.999 6),0.024-24.000 μg· ml-1(r=0.999 6),0.028-28.000μg·ml-1(r=0.999 8),0.034-34.000μg·ml-1(r=0.999 6),0.040-40.000μg·ml-1(r=0.999 7) and 0.050-50. 000 μg·ml-1 (r =0.999 9), respectively. The average recovery was 97.20%, 97.40%, 97.53%, 99. 60%, 98. 78% and 98. 27% and RSD was 0. 89%, 1. 18%, 1. 52%, 1. 49%, 0. 79% and 1. 74%(n=6), respectively. Con-clusion:The method is accurate, suitable, convenient and reproducible, which can be used for the quality control of multi components in Shexiang Baoxin pills.
ABSTRACT
Objective To investigate the effects of the routine needle-withdrawing method and improved needle-withdrawing method? Methods One hundred patients undergoing intravenous transfusion were randomized into the control group and the improvement group (255 times of transfusion ), with 50 cases in each group: the former was treated with routine needle-withdrawing method and the latter with the improved method? Complications after needle-withdruing were compared between the two groups? Result The rates of pains, subcutaneous bleeding or bleeding at the puncture points in the improvement group were all significantly lower than those of the control group (P<0?001)? Conclusion The improved needle-withdrawing method is effective in reducing the rate of post-withdrawal complications and improve the safety of intravenous transfusion?
ABSTRACT
Objective To study the effect of health education on compliance of patients undergoing anticoagulant therapy after cardiac valve replacement? Methods One hundred and six patients undergoing anticoagulant therapy after cardiac valve replacement received enhanced health education after cardiac valve replacement? A self-designed questionnaire was used to investigate their treatment compliance and mastery of related knowledge pre-and postoperatively? Result The mastery of the knowledge related to anticoagulant therapy and the compliance were significantly improved compared to pre-health education(bothP < 0?05)? Conclusion The health education may improve the recognition of anti-coagulant therapy as well as compliance of patients?